7. Completed and protected projects with currently available data
To date, the MCPS research teams in Oxford and UNAM have focused on studying the relevance to cause-specific mortality of major disease risk factors, including diabetes1-3, adiposity4-7, blood pressure8, smoking9 and low levels of education10, and have also published several cross-sectional analyses related to these11-14 and other cardiometabolic risk factors including lipids and other biomarkers15-16. In addition, current analyses (anticipated for publication in 2024/5) will report the relevance of alcohol consumption, physical activity and renal function to cause-specific mortality, as well as the combined relevance of these major disease risk factors to cardiovascular risk. If you are interested in studying any of these risk factors we recommend that you review these published papers (or contact us) to see what has already been, or soon will be, published from the study.
In addition, several areas of research are currently being explored by PhD students or researchers at Oxford and UNAM, and are therefore considered protected until the completion of the project. These include, but are not limited to, studying the genetics of diabetes, kidney function, adiposity, blood pressure, cognitive function and blood lipids, Mendelian randomisation studies of these phenotypes, and use of polygenic risk scores for predicting cardio-metabolic mortality. Applications for projects that overlap significantly with protected projects may require further discussion before approval. This may also be the case where an application overlaps significantly with an external project that has already been approved.
principal Investigator |
project title |
date of first contact |
mcps data request id |
country |
type of data sharing agreement |
| Dr Christina Magnussen | Geographical distribution, global impact and related lifetime risk of classical cardiovascular risk factors on CVD onset | 18/01/2021 | 2021-001 | Germany | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Data-driven socioeconomic clusters reveal inequalities in all-cause and cause specific mortality | 10/05/2021 | 2021-004 | Mexico | Open Access |
| Dr Lorena Orozco | Leveraging the MCPS cohort: towards precision medicine and population genetics in Mexican/Latin American populations | 29/06/2022 | 2022-004 | Mexico | Collaboration |
| Dr Yanink Caro-Vega | Female reproductive history and cancer-related deaths among participants in the Mexico City Prospective Study (MCPS) cohort | 10/08/2022 | 2022-007 | Mexico | Open Access |
| Dr Omar Yaxmehen Bello-Chavolla | Smoking and cause-specific mortality in individuals with diabetes in Mexico: an analysis of the Mexico City Prospective Study | 18/05/2022 | 2022-012-01 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Clinical and sociodemographic determinants of newly diagnosed diabetes in apparently-healthy adults living in Mexico City | 18/05/2022 | 2022-012-02 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | External validation of AnthropoAge as a biological age metric for all-cause and cause-specific mortality. | 18/05/2022 | 2022-012-03 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Metabolomic, anthropometric and sociodemographic characterization of accelerated anthropometric aging | 18/05/2022 | 2022-012-04 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla |
Validation, calibration and metabolomic association of GFR equations in the Mexican population, its risk of mortality from all causes and specific |
18/05/2022 | 2022-012-05 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Prediabetes and cause-specific mortality | 18/05/2022 | 2022-012-06 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | External validation of Globorisk, SCORE, Globorisk-LAC and the Framingham formula for cardiovascular disease and mortality | 18/05/2022 | 2022-012-07 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Prediction of mortality using anthropometric indices (relative fat mass); and visceral adiposity indices, all cause and specific cause mortality. | 18/05/2022 | 022-012-08 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Hypertension phenotypes, all-cause and cause-specific mortality | 18/05/2022 | 022-012-09 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla |
Prediction of cardiovascular mortality according to diabetes endotypes in Mexican individuals, and development of a score to evaluate |
18/05/2022 | 022-012-10 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Inception and validation of a predictive scale for cardiometabolic deaths using a office, biochemical and metabolomic approach | 18/05/2022 | 2022-012-11 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Effect of sociodemographic determinants of social inequalites on preventable and treatable mortality | 18/05/2022 | 2022-012-12 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Lifestyle patterns and their interaction effect with metabolomic risk profiles on the risk of all-cause and cause-specific mortality | 18/05/2022 | 2022-012-13 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Undiagnosed, untreated, and uncontrolled diabetes and high blood pressure and their risk of mortality from all causes and from specific causes | 18/05/2022 | 2022-012-14 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Validation of an atherosclerotic disease-based prediction score for cardiometabolic mortality | 18/05/2022 | 2022-012-15 | Mexico | Collaboration |
| Dr Omar Yaxmehen Bello-Chavolla | Working occupations and their interaction with cardiometabolic risk profiles for all-cause and cause-specific mortality risk | 18/05/2022 | 2022-012-16 | Mexico | Collaboration |
| Dr Gary O'Donovan | Longitudinal associations of the 'weekend warrior' and other physical activity patterns with mortality: the Mexico City Prospective Study | 17/11/2022 | 2022-015 | Colombia | Open Access |
| Dr Mashaal Sohail | Disentangling genes, environment, and their interplay in Mexico City | 16/11/2022 | 2022-016-02 | Mexico | Collaboration |
| Dr Mashaal Sohail | Archaic introgression and complex trait variation in MCPS | 16/11/2022 | 2022-016-01 | Mexico | Open Access |
| Dr Gerson Ferrari | Role of modifiable risk factors on adverse health outcomes: a prospective study using the Mexico City Prospective Study | 15/12/2022 | 2022-020 | Chile | Open Access |
| Dr Claudia Gonzaga-Jauregui | Identification and analysis of medically actionable variants in the Mexican population | 11/01/2023 | 2023-001-01 | Mexico | Open Access |
| Dr Claudia Gonzaga-Jauregui | Identification of genetic variants associated with Early Onset Alzheimer's Disease risk in the Mexican population | 11/01/2023 | 2023-001-02 | Mexico | Open Access |
| Dr Claudia Gonzaga-Jauregui | Identification of genetic variants associated with hereditary cancer in the Mexican population | 11/01/2023 | 2023-001-03 | Mexico | Collaboration |
| Dr Claudia Gonzaga-Jauregui | Identification and analysis of Mendelian disorders associated variation in the Mexican population | 11/01/2023 | 2023-001-04 | Mexico | Open Access |
| Dr Claudia Gonzaga-Jauregui | Identification and analysis of structural variation in the Mexican population | 11/01/2023 | 2023-001-05 | Mexico | Open Access |
| Dr Cristopher Van Hout | Parent of origin effects of genetic determinants of diabetic risk and related traits in the Mexico City Prospective Study | 11/01/2023 | 2023-001-06 | Mexico | Collaboration |
| Dr Cristopher Van Hout | Modeling the relationship between obesity and cancer in the Mexico City Prospective Study | 31/03/2023 | 2023-001-07 | Mexico | Open Access |
| Dr Claudia Gonzaga-Jauregui | Identification of pharmacogenomic variants associated with drug response and metabolism in the Mexican population | 12/04/2023 | 2023-001-08 | Mexico | Open Access |
| Dr Claudia Gonzaga-Jauregui | Identification and analysis of short tandem repeats and their variability in Mexican genomes | 12/04/2023 | 2023-001-09 | Mexico | Open Access |
| Dr Enrique Gomez-Figueroa | Stroke mortality and risk factors in Mexico | 19/01/2023 | 2023-005 | Mexico | Open Access |
| Dr Adrian Soto-Mota | Mortality across different levels of LDL-C in people without other cardiovascular risk factors | 01/02/2023 | 2023-008 | Mexico | Collaboration |
| Dr Vicente Diego Ortega-Del Vecchyo | Impact of natural selection acting on new variants on the MCPS | 16/03/2023 | 2023-011 | Mexico | Open Access |
| Dr Yang Luo | HLA typing, diversity, and association analysis in the Mexico City Prospective Study | 16/03/2023 | 023-012 | England | Oxford Interdepartmental |
| Dr Omar Yaxmehen Bello-Chavolla | Leveraging rare variation, global and local ancestry to develop polygenic risk scores for type 2 diabetes in admixed Americans | 07/06/2023 | 2023-021 | Mexico | Collaboration |
| Dr Osvaldo Máximo Mutchinick Baringoltz | Development of a risk prediction model for myelomeningocele using a candidate gene sequencing panel in Mexican mestizo families | 05/06/2023 | 2023-023 | Mexico | Open Access |
| Dr Gary O'Donovan | What are the associations between ‘diabesity’ and mortality in adults in Mexico? Findings from the Mexico City Prospective Study | 14/08/2023 | 2023-026 | Colombia | Open Access |
| Dr Gary O'Donovan |
Associations between the ‘weekend warrior’ physical activity pattern and screen-detected mild cognitive impairment: findings from the Mexico |
25/08/2023 | 2023-027 | Colombia | Open Access |
| Dr Lorena Orozco | Genetic variants associated with the response to diabetes type 2 treatment | 25/08/2023 | 2023-028 | Mexico | Collaboration |
| Dr Catalina Medina Garcia |
Are there U-shaped associations of HDL-cholesterol and HDL-cholesterol subclasses with mortality? An analysis of more than 40,000 participants in the Mexico City Prospective Study |
07/09/2023 | 2023-029 | Mexico | Open Access |
| Dr Malaquías López Cervantes | Family characteristics related to the presence of obesity in residents of Mexico City | 19/09/2023 | 2023-031 | Mexico | Open Access |
| Prof Peter Visscher | Estimation of between-ancestry genetic differences from analysis of family data in an admixed population | 07/12/2023 | 2023-036 | England | Oxford Interdepartmental |
| Alberto Nordmann Gomes | Prevalence, Management, and Mortality Outcomes of CKD in the Mexico City Prospective Study | 29/01/2024 | 2024-004 | Mexico | Collaboration |
| Dr Gary O'Donovan | Associations between screen-detected cognitive impairment and mortality: findings from the Mexico City Prospective Study | 07/02/2024 | 2024-007 | Colombia | Collaboration |
| Dr Gerson Ferrari | Joint association between physical activity, obesity and all cause and cause specific mortality in Mexican adults | 21/03/2024 | 2024-011 | Chile | Open Access |
| Dr Adrian Rubli | Genetic moderation of the income-health relationship: Evidence from Mexico's elderly cash transfer programme | 07/05/2024 | 2024-013 | Mexico | Open Access |
| Dr Javier Calvo Marin |
Analysis of Cardiovascular Risk Factor and Mortality Among the Elderly in Mexico City and Costa Rica: Insights from the MCPS and CRELES Cohorts |
03/07/2024 | 2024-025 | Costa Rica | Collaboration |
| Dr Gerson Ferrari | Joint association of physical activity and sleep duration with all-cause and cause-specific mortality: a prospective study of Mexican adults | 09/07/2024 | 2024-026 | Chile | Open Access |
| Dr Gerson Ferrari |
Physical activity pattern and all-cause mortality: a prospective study of 150,145 Mexican adults with different health conditions (hypertension |
31/07/2024 | 2024-029 | Chile | Open Access |
| Dr Gary O'Donovan |
Latent class analysis of multimorbidity and its associations with cardiovascular disease, cancer and all-cause mortality in Mexican adults: |
29/08/2024 | 2024-036 | Colombia | Open Access |
| Dr Josep Mercader | G6PD and diabetes complications | 23/08/2024 | 2024-037-01 | USA | Collaboration |
| Dr Josep Mercader | Assessing pathogenicity of monogenic diabetes genes using sequence/TOPMed imputed data | 23/08/2024 | 2024-037-03 | USA | Collaboration |