MRC PHRU Research Fellow
Sarah Clark is a Research Fellow within the NDPH Wolfson Laboratories. She coordinates the research and assay development programme and is a member of the senior laboratory management team. Sarah studied Chemistry at Oxford University and joined the Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU) in 1994 to undertake a D.Phil in Clinical Chemistry and Epidemiology, working on the ISIS-3 case-control study of biochemical risk factors for myocardial infarction.
Sarah’s main areas of research are the design and conduct of methodological studies to establish appropriate sample collection, transport and storage methods for large blood-based epidemiological studies and the development of new analytical methods suitable for high-throughput testing. Examples of projects include the investigation of analyte stability in mailed blood or urine; stabilisation of homocysteine and phosphate in transported blood samples; stability of analytes in long-term frozen samples; development of a modified beta quantification reference method for accurate measurement of LDL-cholesterol; and investigation of assay and sample suitability for measurement of FGF-23.
In addition to supporting CTSU projects, Sarah actively supports collaboration with external groups including the UK Biobank, the Cancer Council of New South Wales and the London School of Hygiene and Tropical Medicine.
The relative and attributable risks of cardia and non-cardia gastric cancer associated with H. pylori infection in China: a case-cohort study
YANG L. et al, (2021), Lancet Public Health