Robin Walters

• Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

  Wain LV. et al, (2017), Nat Genet, 49, 416 - 425

• A Loss-of-Function Variant in CETP Is Associated With Altered Lipid Metabolism but Not With Cardiovascular Disease Incidence in Chinese Adults

  Chen Z. et al, (2016), CIRCULATION, 134, E711 - E711

• Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

  Gan W. et al, (2016), Diabetologia, 59, 1446 - 1457

• The Burden of Hypertension and Associated Risk for Cardiovascular Mortality in China.

  Lewington S. et al, (2016), JAMA Internal Medicine, 176, 524 - 532

• Lipoprotein-Associated Phospholipase A2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults.

  Millwood IY. et al, (2016), J Am Coll Cardiol, 67, 230 - 231

• Blood pressure in relation to general and central adiposity among 500 000 adult Chinese men and women.

  Chen Z. et al, (2015), Int J Epidemiol, 44, 1305 - 1319

• Truncating Homozygous Mutation of Carboxypeptidase E (CPE) in a Morbidly Obese Female with Type 2 Diabetes Mellitus, Intellectual Disability and Hypogonadotrophic Hypogonadism.

  Alsters SI. et al, (2015), PLoS One, 10

• COPD and its association with smoking in the Mainland China: a cross-sectional analysis of 0.5 million men and women from ten diverse areas.

  Kurmi OP. et al, (2015), Int J Chron Obstruct Pulmon Dis, 10, 655 - 665

• Mthfr c677t genotype is not associated with ischaemic heart disease and stroke in a large prospective study in china

  Bennett D. et al, (2014), EUROPEAN HEART JOURNAL, 35, 52 - 52

• Regional variations in the prevalence and misdiagnosis of air flow obstruction in China: baseline results from a prospective cohort of the China Kadoorie Biobank (CKB)

  Kurmi OP. et al, (2014), BMJ Open Respiratory Research, 1

• Associations of blood glucose and prevalent diabetes with risk of cardiovascular disease in 500 000 adult Chinese: the China Kadoorie Biobank.

  Bragg F. et al, (2014), Diabet Med, 31, 540 - 551

• Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity.

  Walters RG. et al, (2013), PLoS One, 8

• Genetic and environmental influences on leukocyte telomere length: studies in Northern Finns reveal gender differences

  Buxton J. et al, (2012), JOURNAL OF MEDICAL GENETICS, 49, S23 - S23

• Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity

  Moustafa JSES. et al, (2012), Hum Mol Genet, 21, 3727 - 3738

• Gene-Targeted Analysis of Copy Number Variants Identifies Three Novel Associations with Coronary Heart Disease Traits

  Costelloe SJ. et al, (2012), Circulation: Cardiovascular Genetics

• Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus.

  Jacquemont S. et al, (2011), Nature, 478, 97 - 102

• famCNV: copy number variant association for quantitative traits in families.

  Eleftherohorinou H. et al, (2011), Bioinformatics, 27, 1873 - 1875

• Childhood obesity is associated with shorter leukocyte telomere length.

  Buxton JL. et al, (2011), J Clin Endocrinol Metab, 96, 1500 - 1505

• cnvHap: an integrative population and haplotype-based multiplatform model of SNPs and CNVs.

  Coin LJ. et al, (2010), Nat Methods, 7, 541 - 546

• A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.

  Walters RG. et al, (2010), Nature, 463, 671 - 675

• Identification and validation of novel genomic CNVs associated with Type 2 diabetes

  Buxton J. et al, (2009), JOURNAL OF MEDICAL GENETICS, 46, S93 - S93

• Elucidating the aetiology of Prader-Willi syndrome: deletion of the HBII-85 class of snoRNA is associated with hyperphagia, obesity and hypogonadism

  de Smith AJ. et al, (2009), JOURNAL OF MEDICAL GENETICS, 46, S83 - S83

• CNVs in Obesity: Uncovering a New Level of Genomic Variation

  Moustafa JSE-S. et al, (2009), JOURNAL OF MEDICAL GENETICS, 46, S91 - S91

• A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism.

  de Smith AJ. et al, (2009), Hum Mol Genet, 18, 3257 - 3265

• Alu elements implicated in the generation of 9/20 CNV deletions investigated by breakpoint sequencing

  de Smith A. et al, (2008), JOURNAL OF MEDICAL GENETICS, 45, S90 - S90

• Small deletion variants have stable breakpoints commonly associated with Alu elements.

  de Smith AJ. et al, (2008), PLoS One, 3

• Human genes involved in copy number variation: mechanisms of origin, functional effects and implications for disease.

  de Smith AJ. et al, (2008), Cytogenet Genome Res, 123, 17 - 26

• Towards an understanding of photosynthetic acclimation.

  Walters RG., (2005), J Exp Bot, 56, 435 - 447

• A mutant of Arabidopsis lacking the triose-phosphate/phosphate translocator reveals metabolic regulation of starch breakdown in the light.

  Walters RG. et al, (2004), Plant Physiol, 135, 891 - 906

• Acclimation of Arabidopsis thaliana to the light environment: the relationship between photosynthetic function and chloroplast composition.

  Bailey S. et al, (2004), Planta, 218, 793 - 802

• Absence of the Lhcb1 and Lhcb2 proteins of the light-harvesting complex of photosystem II - effects on photosynthesis, grana stacking and fitness.

  Andersson J. et al, (2003), Plant J, 35, 350 - 361

• Identification of mutants of Arabidopsis defective in acclimation of photosynthesis to the light environment

  Walters RG. et al, (2003), Plant Physiology, 131, 472 - 481

• Acclimation of Arabidopsis thaliana to the light environment: the existence of separate low light and high light responses.

  Bailey S. et al, (2001), Planta, 213, 794 - 801

• Increasing rice photosynthesis by manipulation of the acclimation and adaptation to light.

  Horton P. et al, (2001), Novartis Found Symp, 236, 117 - 130

• Antisense inhibition of the photosynthetic antenna proteins CP29 and CP26: implications for the mechanism of protective energy dissipation

  Andersson J. et al, (2001), The Plant Cell Online, 13, 1193 - 1204

• Acclimation of Arabidopsis thaliana to the light environment: the role of photoreceptors.

  Walters RG. et al, (1999), Planta, 209, 517 - 527

• Structural and functional heterogeneity in the major light-harvesting complexes of higher plants

  Walters RG. and Horton P., (1999), Photosynthesis research, 61, 77 - 90

• The effects of elevated light on Photosystem II function: A thermoluminescence study

  Walters RG. and Johnson GN., (1997), Photosynthesis research, 54, 169 - 183

• Identification of proton-active residues in a higher plant light-harvesting complex.

  Walters RG. et al, (1996), Proc Natl Acad Sci U S A, 93, 14204 - 14209

• REGULATION OF LIGHT HARVESTING IN GREEN PLANTS.

  Horton P. et al, (1996), Annu Rev Plant Physiol Plant Mol Biol, 47, 655 - 684

• SCIENCE AND DEMOCRACY

  WALTERS R., (1995), NATURE, 375, 10 - 10

• DCCD binds to lumen-exposed glutamate residues in LHCIIc - Implications for the mechanism of photoprotective energy dissipation

  Walters RG. and Horton P., (1995), PHOTOSYNTHESIS: FROM LIGHT TO BIOSPHERE, VOL I, 299 - 302

• Acclimation of Arabidopsis thaliana to the light environment: regulation of chloroplast composition.

  Walters RG. and Horton P., (1995), Planta, 197, 475 - 481

• Acclimation of Arabidopsis thaliana to the light environment: changes in photosynthetic function.

  Walters RG. and Horton P., (1995), Planta, 197, 306 - 312

• Higher plant light-harvesting complexes LHCIIa and LHCIIc are bound by dicyclohexylcarbodiimide during inhibition of energy dissipation.

  Walters RG. et al, (1994), Eur J Biochem, 226, 1063 - 1069

• Regulation of Light Harvesting in Green Plants (Indication by Nonphotochemical Quenching of Chlorophyll Fluorescence).

  Horton P. et al, (1994), Plant Physiol, 106, 415 - 420

• Acclimation of Arabidopsis thaliana to the light environment: changes in composition of the photosynthetic apparatus

  Walters RG. and Horton P., (1994), Planta, 195, 248 - 256

• Theoretical assessment of alternative mechanisms for non-photochemical quenching of PS II fluorescence in barley leaves

  Walters RG. and Horton P., (1993), Photosynthesis research, 36, 119 - 139

• INHIBITION OF DELTA-PH-DEPENDENT CONTROL OF CHLOROPLAST LIGHT HARVESTING BY BINDING OF DCCD TO LHCII

  HORTON P. et al, (1992), PHOTOSYNTHESIS RESEARCH, 34, 121 - 121

• The molecular mechanism of the control of excitation energy dissipation in chloroplast membranes. Inhibition of delta pH-dependent quenching of chlorophyll fluorescence by dicyclohexylcarbodiimide.

  Ruban AV. et al, (1992), FEBS Lett, 309, 175 - 179

• Resolution of components of non-photochemical chlorophyll fluorescence quenching in barley leaves

  Walters RG. and Horton P., (1991), Photosynthesis Research, 27, 121 - 133

• A transposon insertion in the Escherichia coli uvrC gene; UvrC protein is absolutely required for the incision step in excision repair.

  Walters RG. et al, (1988), J Gen Microbiol, 134, 403 - 412

• Fresh fruit consumption and all-cause and cause-specific mortality: findings from the China Kadoorie Biobank

  Du H. et al, International Journal of Epidemiology

• A phenome-wide association study of a lipoproteinassociated phospholipase A2 loss-of-function variant in 90 000 Chinese adults

  Millwood IY., International Journal of Epidemiology

Recent Publications

• Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

  Wain LV. et al, (2017), Nat Genet, 49, 416 - 425

• A Loss-of-Function Variant in CETP Is Associated With Altered Lipid Metabolism but Not With Cardiovascular Disease Incidence in Chinese Adults

  Chen Z. et al, (2016), CIRCULATION, 134, E711 - E711

• Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

  Gan W. et al, (2016), Diabetologia, 59, 1446 - 1457

• The Burden of Hypertension and Associated Risk for Cardiovascular Mortality in China.

  Lewington S. et al, (2016), JAMA Internal Medicine, 176, 524 - 532

• Lipoprotein-Associated Phospholipase A2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults.

  Millwood IY. et al, (2016), J Am Coll Cardiol, 67, 230 - 231