Mike Clarke

BA, DPhil

Director of the Northern Ireland Clinical Trials Unit
Northern Ireland Methodology Hub Lead, Queen’s University, Belfast

Professor Mike Clarke has nearly 30 years’ experience in the design and conduct of rigorous assessments of the effects of interventions through the use of randomised trials and systematic reviews. He joined CTSU in 1989 following a BA in chemistry and while finishing his DPhil on the history and epidemiology of suicide at the University of Oxford. Since then, he has been part of the Secretariat for the breast cancer overview, with a particular focus on the effects of ovarian ablation or suppression for women with early breast cancer. He was Director of the UK Cochrane Centre from 2002 to 2011 and now leads the Northern Ireland Methodology Hub at Queen’s University, Belfast and is Director of the Northern Ireland Clinical Trials Unit.

Recent publications

Using an evidence-based research approach to place your results into context after the study is performed to ensure usefulness of the conclusion.
Journal article

Lund H. et al, (2020), J Clin Epidemiol
Addressing challenges for clinical research responses to emerging epidemics and pandemics: a scoping review.
Journal article

Sigfrid L. et al, (2020), BMC Med, 18
A minimal common outcome measure set for COVID-19 clinical research.
Journal article

WHO Working Group on the Clinical Characterisation and Management of COVID-19 infection None., (2020), Lancet Infect Dis
Addressing political, economic, administrative, regulatory, logistical, ethical, and social challenges to clinical research responses to emerging epidemics and pandemics: a systematic review
Conference paper

Sigfrid L. et al, (2019), LANCET, 394, 86 - 86
Industry funding was associated with increased use of core outcome sets.
Journal article

Kirkham JJ. et al, (2019), Journal of clinical epidemiology, 115, 90 - 97

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