Professor Mike Clarke
- Director of the Northern Ireland Clinical Trials Unit
- Northern Ireland Methodology Hub Lead, Queen’s University, Belfast
Professor Mike Clarke has nearly 30 years’ experience in the design and conduct of rigorous assessments of the effects of interventions through the use of randomised trials and systematic reviews. He joined CTSU in 1989 following a BA in chemistry and while finishing his DPhil on the history and epidemiology of suicide at the University of Oxford. Since then, he has been part of the Secretariat for the breast cancer overview, with a particular focus on the effects of ovarian ablation or suppression for women with early breast cancer. He was Director of the UK Cochrane Centre from 2002 to 2011 and now leads the Northern Ireland Methodology Hub at Queen’s University, Belfast and is Director of the Northern Ireland Clinical Trials Unit.
Addressing political, economic, administrative, regulatory, logistical, ethical, and social challenges to clinical research responses to emerging epidemics and pandemics: a systematic review
Sigfrid L. et al, (2019), LANCET, 394, 86 - 86
Industry funding was associated with increased use of core outcome sets.
Kirkham JJ. et al, (2019), Journal of clinical epidemiology, 115, 90 - 97
Frequency and format of clinical trial results dissemination to patients: a survey of authors of trials indexed in PubMed.
Schroter S. et al, (2019), BMJ Open, 9
A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks-results from the Lassa fever pilot.
Sigfrid L. et al, (2019), BMC Med, 17
Molecular biomarkers and precision medicine in colorectal cancer: a systematic review of health economic analyses.
Henderson R. et al, (2019), Oncotarget, 10, 3408 - 3423