Dr Louisa Gnatiuc
Contact information
AWARDS
The World Heart Federation Salim Yusuf Emerging Leaders Programme 2020
The European Society of Cardiology Educational Grant 2017
Research groups
- Mexico City Prospective Study Estudio Prospectivo de la Ciudad de México
- Causal associations of body composition and disease-specific mortality in contrasting populations
- A GWAS atlas of adiposity traits in Mexicans
- Polygenic risk scores for prediction of cause-specific disease and mortality risk in Mexicans
- Metabolic rate and risk of diabetes, cardiovascular and other diseases in different populations
- An atlas of metabolomic risk factors for specific diseases and mortality in Mexicans
- Risk scores for prediction of diabetes and its complications
- Novel biomarkers and risk for co-mordbidities of adiposity and diabetes in the UK Biobank
- Adiposity and risk of respiratory diseases
- The relationship between COVID-19 and cardio-metabolic health risks
- Biomarker signatures of lifestyle determinants for preventable cardio-metabolic diseases
Websites
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Mexico City Prospective Study
Cohort Study
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International Advisory Board
The Lancet Global Health
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Nucleus Member, Deputy Prevention Implementation Committee
European Society of Preventive Cardiology
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Module Lead and Lecturer in Epidemiology
University of Oxford
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Associate Editor
Global Heart Journal
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External Lecturer in Chronic Disease Epidemiology
London School of Hygiene and Tropical Medicine
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Honorary Research Associate
Imperial College London, NHLI
Louisa Gnatiuc Friedrichs
BA, DLSHTM, MSc, DPhil
Senior Epidemiologist
With experience in acute medicine, epidemiology and public health in Europe, Africa, Asia and South America, Louisa is passionate about population health. Trained in epidemiology and population health at the University of Oxford and the London School of Hygiene & Tropical Medicine, her primary interests include conventional and genetic determinants of vasculo-metabolic diseases, and novel disease models. Her work focuses on the effects of adiposity, diabetes and hypertension on premature cardiometabolic mortality in the Mexico City Prospective Study, the Prospective Studies Collaboration and the UK Biobank.
Louisa is a member of the International Advisory Board for Lancet Global Health, a Nucleus Member of the European Society for Preventive Cardiology and an editor for the Global Heart Journal. She preserves a keen interest in teaching, research of under-studied populations where the burden of preventable vasculo-metabolic risk is increasing,and collaboration with multi-national research programs.
Her expertise comprises design, conduct and analysis of large multi-centric surveys, cohort studies, biobanks, and follow-up through surveillance and vital registries. Previous roles involved coordination of British, European and global epidemiological studies with Imperial College London and the Medical Research Council, advisory for the Department of Health and Pharma.
Outside work, she likes arts, photography and world cuisines.
Key publications
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Diabetes and Cause-Specific Mortality in Mexico City.
Journal article
Alegre-Díaz J. et al, (2016), N Engl J Med, 375, 1961 - 1971
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General and Abdominal Adiposity and Mortality in Mexico City: A Prospective Study of 150 000 Adults.
Journal article
Gnatiuc L. et al, (2019), Ann Intern Med, 171, 397 - 405
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Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Journal article
Ziyatdinov A. et al, (2023), Nature, 622, 784 - 793
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Metabolic profiling of MRI-measured liver fat in the UK Biobank.
Journal article
Gnatiuc Friedrichs L. et al, (2023), Obesity (Silver Spring), 31, 1121 - 1132
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Sex-specific relevance of diabetes to occlusive vascular and other mortality: a collaborative meta-analysis of individual data from 980 793 adults from 68 prospective studies.
Journal article
Prospective Studies Collaboration and Asia Pacific Cohort Studies Collaboration None., (2018), Lancet Diabetes Endocrinol, 6, 538 - 546
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Abdominal and gluteo-femoral markers of adiposity and risk of vascular-metabolic mortality in a prospective study of 150 000 Mexican adults.
Journal article
Gnatiuc L. et al, (2022), Eur J Prev Cardiol, 29, 730 - 738
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Changes in the Diagnosis and Management of Diabetes in Mexico City Between 1998-2004 and 2015-2019.
Journal article
Aguilar-Ramirez D. et al, (2021), Diabetes Care, 44, 944 - 951
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Adiposity and NMR-measured lipid and metabolic biomarkers among 30,000 Mexican adults.
Journal article
Aguilar-Ramirez D. et al, (2022), Commun Med (Lond), 2
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Body composition and mortality from vascular or metabolic causes among 150,000 participants in the Mexico City Prospective Study
Conference paper
Gnatiuc L. et al, (2019), EUROPEAN HEART JOURNAL, 40, 2412 - 2412
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Effect of diabetes duration and glycaemic control on 14-year cause-specific mortality in Mexican adults: a blood-based prospective cohort study.
Journal article
Herrington WG. et al, (2018), Lancet Diabetes Endocrinol, 6, 455 - 463
Recent publications
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A Mendelian randomization study of the effect of body mass index on 52 causes of death among 125 000 Mexican adults with admixed ancestry.
Journal article
Gnatiuc Friedrichs L. et al, (2025), Int J Epidemiol, 54
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Prediabetes and risk of all-cause and cause-specific mortality: a prospective study of 114,062 adults in Mexico City.
Journal article
Fermín-Martínez CA. et al, (2025), J Clin Endocrinol Metab
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Cognitive impairment at older ages among 8000 men and women living in Mexico City: a cross-sectional analyses of a prospective study.
Journal article
González-Carballo C. et al, (2024), BMC Public Health, 24
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Blood Pressure, eGFR, and Kidney Mortality in Mexico: A Prospective Study of 150,000 Adults
Conference paper
Zhu D., (2024)
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Blood Pressure, eGFR, and Kidney Mortality in Mexico: A Prospective Study of 150,000 Adults
Journal article
Zhu D. et al, (2024), Journal of the American Society of Nephrology, 35
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Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Journal article
Ziyatdinov A. et al, (2024), Nature, 626
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Polygenic prediction of coronary heart disease among 130,000 Mexican adults
Preprint
Liu T. et al, (2024)
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Genotyping, sequencing and analysis of 140,000 adults from Mexico City
Journal article
TORRES J. et al, (2023), Nature
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Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Journal article
Ziyatdinov A. et al, (2023), Nature, 622, 784 - 793
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Educational and social inequalities and cause-specific mortality in Mexico City: a prospective study.
Journal article
Addey T. et al, (2023), Lancet Public Health, 8, e670 - e679