Federico Murgia
Bioinformatician
Federico is a bioinformatician with longstanding experience in bioinformatics, genetics and genetic epidemiology.
After a degree in biological sciences from the University of Cagliari and a postgraduate research degree in bioinformatics applied to personalised medicine, Federico worked for several years as a biostatistician and bioinformatician for public and private organisations. He focused his research activity on the application of genetic and genomic methods to study complex traits in both general and genetically isolated populations.
He has extensive experience in the processing of large-scale human genetic datasets, the analysis of exome/whole sequencing data, GWAS, functional annotation, development of automated pipelines and data visualisation.
He joined CTSU in 2018, where he's involved in discovery and in-depth exploration of genomic predictors for vascular disease and its risk factors, working on a wealth of projects related CTSU's vascular mega-trials, biobanks and large studies.
Recent publications
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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.
Journal article
Aragam KG. et al, (2022), Nat Genet
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Determining the Relationship Between Blood Pressure, Kidney Function, and Chronic Kidney Disease: Insights From Genetic Epidemiology.
Journal article
Staplin N. et al, (2022), Hypertension
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Are polygenic risk scores for systolic blood pressure and LDL-cholesterol associated with treatment effectiveness, and clinical outcomes among those on treatment?
Journal article
Tapela NM. et al, (2021), Eur J Prev Cardiol
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Assessment of the causal relevance of ECG parameters for risk of atrial fibrillation: A mendelian randomisation study.
Journal article
Gajendragadkar PR. et al, (2021), PLoS Med, 18
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Genome-wide scans of myopia in Pennsylvania Amish families reveal significant linkage to 12q15, 8q21.3 and 5p15.33.
Journal article
Musolf AM. et al, (2019), Human genetics, 138, 339 - 354