Influential research
Our reports are published in major medical journals and by March 2025 had been cited more than 37,500 times. The group’s findings are widely used in consensus statements, clinical guidelines, decision aids, and treatment decisions around the world. They have influenced the care of millions of women making a major contribution to the large falls in worldwide breast cancer mortality seen over the last four decades. The EBCTCG results help define the treatment questions to be tested in future trials and, by developing and demonstrating appropriate methods for individual studies and systematic reviews, influences research strategies in other areas of health care.
Latest news
Privacy Notice
We take the confidentiality of our data extremely seriously. Read the EBCTCG Privacy Notice to find out how we treat data from clinical trials.
EBCTCG publications and findings
Explore research publications and findings from the Early Breast Cancer Trialists’ Collaborative Group
Current and Planned Projects
The international Steering Committee of the EBCTCG meets annually to discuss current and emerging results from EBCTCG meta-analyses and to prioritise future meta-analyses. Emerging results include:
- comparing different types and methods of administration of chemotherapy
- comparison of 10 vs 5 years of endocrine therapy (tamoxifen or AI)
- ovarian suppression in the presence and absence of chemotherapy
- trials of trastuzumab and other biological agents (eg bevacizumab)
- assessing the benefits and risks of different radiotherapy techniques
- establishing appropriate primary and adjuvant therapy for older women
- reviews of tumour characteristics (e.g, rate of proliferation, immune response, gene expression) and of body-mass index to risk of breast cancer recurrence.
Funding
The EBCTCG is funded by Oxford Population Health/CTSU, and the Breast Cancer Research Foundation. It has also been funded by Cancer Research UK and the UK Medical Research Council We receive no funding from any commercial organisations.
FURTHER INFORMATION
History of EBCTCG results prior to 2005
Original methods for EBCTCG meta-analyses
EBCTCG variables and data format
CTSU Clinical Trial Follow Up Service Privacy Notice
EBCTCG Update slides (PowerPoint)