7. Completed and protected projects with currently available data
To date, the MCPS research teams in Oxford and UNAM have focused on studying the relevance to cause-specific mortality of major disease risk factors, including diabetes,1-5 adiposity,6-10 blood pressure,11,12 smoking,13 low levels of education14 and alcohol consumption.15 We have also published several cross-sectional analyses related to these16-19 and other cardiometabolic risk factors including lipids and other biomarkers.20-21 In addition, current analyses (anticipated for publication in 2025/6) will report the relevance of physical activity and renal function to cause-specific mortality, as well as the combined relevance of these major disease risk factors to cardiovascular risk. If you are interested in studying any of these risk factors we recommend that you review these published papers (or contact us) to see what has already been, or soon will be, published from the study.
In addition, several areas of research are currently being explored by PhD students or researchers at Oxford and UNAM, and are therefore considered protected until the completion of the project. These include, but are not limited to, studying the genetics of diabetes, kidney function, adiposity, blood pressure, cognitive function and blood lipids, Mendelian randomisation studies of these phenotypes, and use of polygenic risk scores for predicting cardio-metabolic mortality. We are particularly focused on studying genetic admixture and/or local ancestry in the context of cardiometabolic traits. Applications for projects that overlap significantly with protected projects may therefore require further discussion before approval.
External projects (open access and collaborations) that have been approved and have an access agreement in place are listed below (last updated 24 April 2026).
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Principal Investigator: Dr Christina Magnussen |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Data-driven socioeconomic clusters reveal inequalities in all-cause and cause specific mortality Date of first contact: 10/05/2021 MCPS data request ID: 2021-004 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Lorena Orozco Project title: Leveraging the MCPS cohort: towards precision medicine and population genetics in Mexican/Latin American populations Date of first contact: 29/06/2022 MCPS data request ID: 2022-004 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Yanink Caro-Vega Project title: Female reproductive history and cancer-related deaths among participants in the Mexico City Prospective Study (MCPS) cohort Date of first contact: 10/08/2022 MCPS data request ID: 2022-007 Country: Mexico Type of data sharing agreement: Open Access |
|
Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Clinical and sociodemographic determinants of newly diagnosed diabetes in apparently-healthy adults living in Mexico City Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-02 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: External validation of AnthropoAge as a biological age metric for all-cause and cause-specific mortality. Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-03 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Metabolomic, anthropometric and sociodemographic characterization of accelerated anthropometric aging Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-04 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Validation, calibration and metabolomic association of GFR equations in the Mexican population, its risk of mortality from all causes and specific causes, and in combination with ENSANUT. Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-05 Country: Mexico Type of data sharing agreement: Collaboration Publications: https://pubmed.ncbi.nlm.nih.gov/41385295 |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Prediabetes and cause-specific mortality Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-06 Country: Mexico Type of data sharing agreement: Collaboration Publications: https://pubmed.ncbi.nlm.nih.gov/40208106 |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: External validation of Globorisk, SCORE, Globorisk-LAC and the Framingham formula for cardiovascular disease and mortality Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-07 Country: Mexico Type of data sharing agreement: Collaboration Publications: https://pubmed.ncbi.nlm.nih.gov/41732703 |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Prediction of mortality using anthropometric indices (relative fat mass); and visceral adiposity indices, all cause and specific cause mortality. Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-08 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Hypertension phenotypes, all-cause and cause-specific mortality Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-09 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Prediction of cardiovascular mortality according to diabetes endotypes in Mexican individuals, and development of a score to evaluate cardiovascular risk in Mexican adults with diabetes Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-10 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Inception and validation of a predictive scale for cardiometabolic deaths using a office, biochemical and metabolomic approach Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-11 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Effect of sociodemographic determinants of social inequalites on preventable and treatable mortality Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-12 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Lifestyle patterns and their interaction effect with metabolomic risk profiles on the risk of all-cause and cause-specific mortality Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-13 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Undiagnosed, untreated, and uncontrolled diabetes and high blood pressure and their risk of mortality from all causes and from specific causes Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-14 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Validation of an atherosclerotic disease-based prediction score for cardiometabolic mortality Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-15 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Working occupations and their interaction with cardiometabolic risk profiles for all-cause and cause-specific mortality risk Date of first contact: 18/05/2022 MCPS data request ID: 2022-012-16 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Gary O'Donovan Project title: Longitudinal associations of the 'weekend warrior' and other physical activity patterns with mortality: the Mexico City Prospective Study Date of first contact: 17/11/2022 MCPS data request ID: 2022-015 Country: Colombia Type of data sharing agreement: Open Access Publications: https://pubmed.ncbi.nlm.nih.gov/38302280 ; https://pubmed.ncbi.nlm.nih.gov/39929380 ; https://pubmed.ncbi.nlm.nih.gov/39472031 |
| Principal Investigator: Dr Mashaal Sohail Project title: Archaic introgression and complex trait variation in MCPS Date of first contact: 16/11/2022 MCPS data request ID: 2022-016-01 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Mashaal Sohail Project title: Disentangling genes, environment, and their interplay in Mexico City Date of first contact: 16/11/2022 MCPS data request ID: 2022-016-02 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Gerson Ferrari Project title: Role of modifiable risk factors on adverse health outcomes: a prospective study using the Mexico City Prospective Study Date of first contact: 15/12/2022 MCPS data request ID: 2022-020 Country: Chile Type of data sharing agreement: Open Access Publications: https://pubmed.ncbi.nlm.nih.gov/38408614 ; https://pubmed.ncbi.nlm.nih.gov/40596691 ; https://pubmed.ncbi.nlm.nih.gov/39918450 |
| Principal Investigator: Dr Claudia Gonzaga-Jauregui Project title: Identification and analysis of medically actionable variants in the Mexican population Date of first contact: 11/01/2023 MCPS data request ID: 2023-001-01 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Claudia Gonzaga-Jauregui Project title: Identification of genetic variants associated with Early Onset Alzheimer's Disease risk in the Mexican population Date of first contact: 11/01/2023 MCPS data request ID: 2023-001-02 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Claudia Gonzaga-Jauregui Project title: Identification of genetic variants associated with hereditary cancer in the Mexican population Date of first contact: 11/01/2023 MCPS data request ID: 2023-001-03 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Claudia Gonzaga-Jauregui Project title: Identification and analysis of Mendelian disorders associated variation in the Mexican population Date of first contact: 11/01/2023 MCPS data request ID: 2023-001-04 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Claudia Gonzaga-Jauregui Project title: Identification and analysis of structural variation in the Mexican population Date of first contact: 11/01/2023 MCPS data request ID: 2023-001-05 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Cristopher Van Hout Project title: Parent of origin effects of genetic determinants of diabetic risk and related traits in the Mexico City Prospective Study Date of first contact: 11/01/2023 MCPS data request ID: 2023-001-06 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Cristopher Van Hout Project title: Modelling the relationship between obesity and cancer in the Mexico City Prospective Study Date of first contact: 31/03/2023 MCPS data request ID: 2023-001-07 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Claudia Gonzaga-Jauregui Project title: Identification of pharmacogenomic variants associated with drug response and metabolism in the Mexican population Date of first contact: 12/04/2023 MCPS data request ID: 2023-001-08 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Claudia Gonzaga-Jauregui Project title: Identification and analysis of short tandem repeats and their variability in Mexican genomes Date of first contact: 12/04/2023 MCPS data request ID: 2023-001-09 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Enrique Gomez-Figueroa Project title: Stroke mortality and risk factors in Mexico Date of first contact: 19/01/2023 MCPS data request ID: 2023-005 Country: Mexico Type of data sharing agreement: Open Access Publications: https://pubmed.ncbi.nlm.nih.gov/39151103 |
| Principal Investigator: Dr Adrian Soto-Mota Project title: Mortality across different levels of LDL-C in people without other cardiovascular risk factors Date of first contact: 01/02/2023 MCPS data request ID: 2023-008 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Vicente Diego Ortega-Del Vecchyo Project title: Impact of natural selection acting on new variants on the MCPS Date of first contact: 16/03/2023 MCPS data request ID: 2023-011 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Yang Luo Project title: HLA typing, diversity, and association analysis in the Mexico City Prospective Study Date of first contact: 16/03/2023 MCPS data request ID: 2023-012 Country: UK Type of data sharing agreement: Oxford Interdepartmental |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Leveraging rare variation, global and local ancestry to develop polygenic risk scores for type 2 diabetes in admixed Americans Date of first contact: 07/06/2023 MCPS data request ID: 2023-021 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Osvaldo Máximo Mutchinick Baringoltz Project title: Development of a risk prediction model for myelomeningocele using a candidate gene sequencing panel in Mexican mestizo families Date of first contact: 05/06/2023 MCPS data request ID: 2023-023 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Gary O'Donovan Project title: What are the associations between ‘diabesity’ and mortality in adults in Mexico? Findings from the Mexico City Prospective Study Date of first contact: 14/08/2023 MCPS data request ID: 2023-026 Country: Colombia Type of data sharing agreement: Open Access Publications: https://pubmed.ncbi.nlm.nih.gov/38439662 |
| Principal Investigator: Dr Fanny Petermann-Rocha Project title: Associations between the ‘weekend warrior’ physical activity pattern and screen-detected mild cognitive impairment: findings from the Mexico City Prospective Study. Date of first contact: 25/08/2023 MCPS data request ID: 2023-027 Country: Chile Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Lorena Orozco Project title: Genetic variants associated with the response to diabetes type 2 treatment Date of first contact: 25/08/2023 MCPS data request ID: 2023-028 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Catalina Medina Garcia Project title: Are there U-shaped associations of HDL-cholesterol and HDL-cholesterol subclasses with mortality? An analysis of more than 40,000 participants in the Mexico City Prospective Study Date of first contact: 07/09/2023 MCPS data request ID: 2023-029 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Malaquías López Cervantes Project title: Family characteristics related to the presence of obesity in residents of Mexico City Date of first contact: 19/09/2023 MCPS data request ID: 2023-031 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Prof Peter Visscher Project title: Estimation of between-ancestry genetic differences from analysis of family data in an admixed population Date of first contact: 07/12/2023 MCPS data request ID: 2023-036 Country: UK Type of data sharing agreement: Oxford Interdepartmental |
| Principal Investigator: Prof Gregorio Obrador Vera Project title: Prevalence, Management, and Mortality Outcomes of CKD in the Mexico City Prospective Study Date of first contact: 29/01/2024 MCPS data request ID: 2024-004 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Elizabeth Atkinson Project title: A collaboration to test TRACTOR-MIX on MCPS data Date of first contact: 05/02/2024 MCPS data request ID: 2024-006 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Gary O'Donovan Project title: Associations between screen-detected cognitive impairment and mortality: findings from the Mexico City Prospective Study Date of first contact: 07/02/2024 MCPS data request ID: 2024-007 Country: Colombia Type of data sharing agreement: Collaboration |
| Principal Investigator: Evelia Apolinar-Jiménez Project title: Associations of the American Heart Association’s Life’s Essential 8 score with morbidity and mortality in Mexico: findings from the Mexico City Prospective Study Date of first contact: 19/03/2024 MCPS data request ID: 2024-009 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Gerson Ferrari Project title: Joint association between physical activity, obesity and all cause and cause specific mortality in Mexican adults Date of first contact: 21/03/2024 MCPS data request ID: 2024-011 Country: Chile Type of data sharing agreement: Open Access |
| Principal Investigator: Prof Janitza L. Montalvo-Ortiz Project title: Comprehensive functional analysis of copy number variants in Major Depressive Disorder in Latin American population Date of first contact: 26/04/2024 MCPS data request ID: 2024-012 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Adrian Rubli Project title: Genetic moderation of the income-health relationship: Evidence from Mexico's elderly cash transfer program Date of first contact: 07/05/2024 MCPS data request ID: 2024-013 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Magdalena Sevilla Project title: Metabolomic signatures of type 2 diabetes genetic subtypes and their association with social determinants of health Date of first contact: 12/06/2024 MCPS data request ID: 2024-020-01 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Magdalena Sevilla Project title: Genetic and non-genetic determinants of metabolomic profiles and their associations with cardiometabolic disease and mortality Date of first contact: 12/06/2024 MCPS data request ID: 2024-020-02 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Javier Calvo Marin Project title: Analysis of Cardiovascular Risk Factor and Mortality Among the Elderly in Mexico City and Costa Rica: Insights from the MCPS and CRELES Cohorts Date of first contact: 03/07/2024 MCPS data request ID: 2024-025 Country: Costa Rica Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Gerson Ferrari Project title: Joint association of physical activity and sleep duration with all-cause and cause-specific mortality: a prospective study of Mexican adults Date of first contact: 09/07/2024 MCPS data request ID: 2024-026 Country: Chile Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Gerson Ferrari Project title: Physical activity pattern and all-cause mortality: a prospective study of 150,145 Mexican adults with different health conditions (hypertension and diabetes mellitus) Date of first contact: 31/07/2024 MCPS data request ID: 2024-029 Country: Chile Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Carolina Ochoa Rosales Project title: Biomarkers of Allostatic Load in Dementia: A Systematic Review and Meta-Analysis Date of first contact: 30/07/2024 MCPS data request ID: 2024-030 Country: Chile Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Carolina Ochoa Rosales Project title: Metabolites associated with cognitive impairment or dementia in Latin America: a systematic review and meta-analysis. Date of first contact: 01/08/2024 MCPS data request ID: 2024-031 Country: Chile Type of data sharing agreement: Collaboration |
| Principal Investigator: Valerie Gunchick Project title: Genome-wide association study (GWAS) for biliary tract cancer (BTC). Date of first contact: 01/08/2024 MCPS data request ID: 2024-032 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Fanny Petermann-Rocha Project title: Latent class analysis of multimorbidity and its associations with cardiovascular disease, cancer and all-cause mortality in Mexican adults: findings from the Mexico City Prospective Study Date of first contact: 29/08/2024 MCPS data request ID: 2024-036 Country: Chile Type of data sharing agreement: Open Access Publications: https://pubmed.ncbi.nlm.nih.gov/40709636 |
| Principal Investigator: Dr Josep Mercader Project title: G6PD and diabetes complications Date of first contact: 23/08/2024 MCPS data request ID: 2024-037-01 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Josep Mercader Project title: Assessing pathogenicity of monogenic diabetes genes using sequence/TOPMed imputed data Date of first contact: 23/08/2024 MCPS data request ID: 2024-037-03 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Catalina Medina Garcia Project title: Frailty index and its association with cardiovascular disease and all-cause mortality in Mexican adults: findings from the Mexico City Prospective Study Date of first contact: 09/09/2024 MCPS data request ID: 2024-038 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Prof Janitza L. Montalvo-Ortiz Project title: Meta-analysis of genome-wide association studies of smoking traits in the Latin American Genomics Consortium (LAGC) Date of first contact: 09/09/2024 MCPS data request ID: 2024-041 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Prof Paolo Boffetta Project title: Using large-scale cohort studies to identify lifetime, environmental and occupational determinants of healthy ageing Date of first contact: 19/09/2024 MCPS data request ID: 2024-042 Country: Italy Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Steven Hageman Project title: Systematic recalibration and external validation of the SCORE2 risk model to the Latin American clinical practice Date of first contact: 04/11/2024 MCPS data request ID: 2024-045 Country: The Netherlands Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Gretchen Saunders Project title: Collaboration with GSCAN (GWAS & Sequencing Consortium of alcohol and Nicotine use) Date of first contact: 01/11/2024 MCPS data request ID: 2024-046 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Rodrigo Garcia-Cerde Project title: Transgenerational Impacts of Social Determinants of Health in Mexican Adults: A Cohort-Based Study Date of first contact: 11/11/2024 MCPS data request ID: 2024-047 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Enrique Gomez-Figueroa Project title: Development of a Predictive Model for Cerebrovascular Mortality Using Medical Data from MCPS: Integrating Machine Learning Techniques Date of first contact: 18/11/2024 MCPS data request ID: 2024-048 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Ruth Selene Fuentes Garcia Project title: Risk equations for complications related to Type 2 Diabetes Mellitus Date of first contact: 05/12/2024 MCPS data request ID: 2024-051 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Lorena Orozco Project title: Mitochondrial biomarkers and cardiometabolic diseases: MCPS cohort Date of first contact: 17/12/2024 MCPS data request ID: 2024-052 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Gerson Ferrari Project title: Association of plasma metabolites, lifestyle risk factors and cardiometabolic conditions with all-cause and cause-specific mortality. Date of first contact: 30/01/2025 MCPS data request ID: 2025-005 Country: Chile Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Gerson Ferrari Project title: Genetic composition and physical activity levels in Mexican adults Date of first contact: 30/01/2025 MCPS data request ID: 2025-006 Country: Chile Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Edgar Denova Gutierrez Project title: Omega-3 and omega-6 polyunsaturated fatty acids and the risk of all-cause and cause-specific mortality in the Mexico City Prospective Study Date of first contact: 04/02/2025 MCPS data request ID: 2025-008 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Sean Joseph Jurgens Project title: Improving the genomic prediction of atrial fibrillation and heart failure across populations Date of first contact: 17/02/2025 MCPS data request ID: 2025-011 Country: The Netherlands Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Fabiola Mabel Del Razo Olvera Project title: Gene-Environment Interaction: Impact of the SLC16A11 Haplotype, ABCA1 and HNF1A variants on Metabolic Diseases, Metabolic and Environmental Factors in Mexican Adults. Date of first contact: 07/04/2025 MCPS data request ID: 2025-015 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Ana Lucía Yáñez Félix Project title: Analysis of the Allelic Frequency of Single Nucleotide Variants in Genes Related to Coagulation Disorders Based on Databases of the General Mexican Population and Their Association in Women With Recurrent Pregnancy Loss Date of first contact: 05/05/2025 MCPS data request ID: 2025-030 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Wenjian Bi Project title: Scalable, accurate, and universal analysis frameworks for large-scale genetic association studies in an admixed population Date of first contact: 07/05/2025 MCPS data request ID: 2025-039 Country: China Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Yi Feng Project title: MCPS-MED: A Multimorbidity-Driven Risk Modelling Framework for Predicting Disease Trajectories and Comorbidity Networks Using MCPS Data Date of first contact: 07/05/2025 MCPS data request ID: 2025-040 Country: China Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Cancan Cui Project title: TyG Index, Metabolomic Profiles, and All-Cause/Cardiovascular Mortality in the Mexico Date of first contact: 07/05/2025 MCPS data request ID: 2025-041 Country: China Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Xiang Gao Project title: Gene–Metabolite Interactions in the Development of metabolic diseases Date of first contact: 14/05/2025 MCPS data request ID: 2025-047 Country: China Type of data sharing agreement: Open Access |
| Principal Investigator: Duncan Robertson Project title: Enhancing analysis of demographic history and complex traits in the MCPS cohort using ancestral recombination graphs Date of first contact: 16/05/2025 MCPS data request ID: 2025-050 Country: UK Type of data sharing agreement: Oxford Interdepartmental |
| Principal Investigator: Dr Daniel Benjamín Elías López Project title: Prevalence and Phenotypic Expression of Dysbetalipoproteinemia in Mexican Population and Its Association with Cardiometabolic and Atherosclerotic Cardiovascular Risk Date of first contact: 02/06/2025 MCPS data request ID: 2025-056 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Evaluating the utility of integrating genomic data into diabetes subtype classifications to predict cardiovascular risk and differentiate pathophysiological mechanisms in Mexican individuals with diabetes Date of first contact: 25/06/2025 MCPS data request ID: 2025-058 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla Project title: Characterizing the genomic architecture and pathophysiology of biological and accelerated aging in Mexican adults using AnthropoAge Date of first contact: 25/06/2025 MCPS data request ID: 2025-059 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Prof Johannes Kettunen Project title: Trans-ethnic GWAS meta-analysis of NMR metabolic traits Date of first contact: 18/06/2025 MCPS data request ID: 2025-060 Country: Finland Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Carlos Celis-Morales Project title: Health-related traits, lifestyle, and mortality risk in healthy and multimorbid populations: evidence from the Mexico City Study Date of first contact: 18/07/2025 MCPS data request ID: 2025-063 Country: UK Type of data sharing agreement: Open Access |
| Principal Investigator: Prof Yun Tan Project title: Prediction and Potential Preventive Targets for Hematologic Malignancies Using Preclinical Plasma Metabolomics and Proteomics Date of first contact: 25/07/2025 MCPS data request ID: 2025-064 Country: China Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Ana Luisa Sosa Ortiz Project title: Exploration and comparison of exposure to air pollutants and occupation in two boroughs of Mexico City and their association with cognitive decline. Date of first contact: 25/08/2025 MCPS data request ID: 2025-071 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Cristopher Van Hout Project title: Current methods in epidemiology for the identification of relevant factors and risk prediction of common diseases in a Mexico City population Date of first contact: 04/09/2025 MCPS data request ID: 2025-075 Country: Mexico Type of data sharing agreement: Open Access |
| Principal Investigator: Dr Mariaelisa Graff Project title: Phenotypic consequences of lipoprotein(a) across populations Date of first contact: 16/09/2025 MCPS data request ID: 2025-077 Country: USA Type of data sharing agreement: Collaboration |
| Principal Investigator: Prof Ping Zeng Project title: Identification of risk factors, integration of multi-omics features, and genetic risk prediction in complex diseases Date of first contact: 18/09/2025 MCPS data request ID: 2025-078 Country: China Type of data sharing agreement: Open Access |
| Principal Investigator: Prof Inês Barroso Project title: The Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Date of first contact: 22/09/2025 MCPS data request ID: 2025-079 Country: UK Type of data sharing agreement: Collaboration |
| Principal Investigator: Prof Andrew Morris Project title: The Type 2 Diabetes Global Genetics Initiative (T2DGGI) Date of first contact: 22/09/2025 MCPS data request ID: 2025-080 Country: UK Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Stefan Blankenburg Project title: Impact of Exposomal, Genetic and Classical Cardiovascular Risk Factors on Cardiovascular Disease and All-cause Mortality Date of first contact: 27/08/2025 MCPS data request ID: 2025-081-01 Country: Germany Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Stefan Blankenburg Project title: Target-trial emulation of blood-pressure–mediated cardiovascular risk reduction in the general population Date of first contact: 27/08/2025 MCPS data request ID: 2025-081-02 Country: Germany Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Stefan Blankenburg Project title: Global Effect of Modifiable Lipid Concentrations on Cardiovascular Risk and All-Cause Mortality in the Population Date of first contact: 27/08/2025 MCPS data request ID: 2025-081-03 Country: Germany Type of data sharing agreement: Collaboration |
| Principal Investigator: Prof Johannes Kettunen Project title: The role of PKHD1L1 in female infertility Date of first contact: 22/09/2025 MCPS data request ID: 2025-082 Country: Finland Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Isela Esther Juárez-Rojop Project title: Mapping the pleiotropic architecture of the genetic risk of mental disorders in the Mexican population Date of first contact: 24/09/2025 MCPS data request ID: 2025-083 Country: Mexico Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Gibran Hemani Project title: Family-based GWAS of complex traits Date of first contact: 28/10/2025 MCPS data request ID: 2025-087 Country: UK Type of data sharing agreement: Collaboration |
| Principal Investigator: Dr Christiana Kartsonaki Project title: Predicting risk of death from common cancers Date of first contact: 10/11/2025 MCPS data request ID: 2025-089 Country: UK Type of data sharing agreement: Oxford Interdepartmental |
| Principal Investigator: Dr Christiana Kartsonaki Project title: Lung Cancer Summary Statistics Date of first contact: 15/12/2025 MCPS data request ID: 2025-092 Country: UK Type of data sharing agreement: Oxford Interdepartmental |
| Principal Investigator: Prof YuanYuan Kong Project title: Investigating the multi-omics, environmental and clinical determinants of Liver diseases and the potential relationships with other diseases Date of first contact: 04/01/2026 MCPS data request ID: 2026-001 Country: China Type of data sharing agreement: Open Access |
References
- Alegre-Díaz, Herrington, López-Cervantes et al. Diabetes and cause-specific mortality in Mexico City. New Engl J Med 2016; 375: 1961-1971.
- Herrington, Alegre-Díaz, Wade et al. Effect of diabetes duration and glycaemic control on 14-year cause-specific mortality in Mexican adults: a blood-based prospective cohort study. Lancet Diab Endocrinol 2018; 6: 455-463.
- Bragg, Kuri-Morales, Berumen et al. Diabetes and infectious disease mortality in Mexico City. BMJ Open Diab Res Care 2023; 11: e003199.
- Bragg, Kuri-Morales, Trichia et al. Type 2 diabetes and cause-specific mortality in Mexico City: a Mendelian randomization analysis. Lancet Reg Health Am 2025; 45: 101082.
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