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7. Completed and protected projects with currently available data

To date, the MCPS research teams in Oxford and UNAM have focused on studying the relevance to cause-specific mortality of major disease risk factors, including diabetes,1-5 adiposity,6-10 blood pressure,11,12 smoking,13 low levels of education14 and alcohol consumption.15 We have also published several cross-sectional analyses related to these16-19 and other cardiometabolic risk factors including lipids and other biomarkers.20-21 In addition, current analyses (anticipated for publication in 2025/6) will report the relevance of physical activity and renal function to cause-specific mortality, as well as the combined relevance of these major disease risk factors to cardiovascular risk. If you are interested in studying any of these risk factors we recommend that you review these published papers (or contact us) to see what has already been, or soon will be, published from the study.

In addition, several areas of research are currently being explored by PhD students or researchers at Oxford and UNAM, and are therefore considered protected until the completion of the project. These include, but are not limited to, studying the genetics of diabetes, kidney function, adiposity, blood pressure, cognitive function and blood lipids, Mendelian randomisation studies of these phenotypes, and use of polygenic risk scores for predicting cardio-metabolic mortality. We are particularly focused on studying genetic admixture and/or local ancestry in the context of cardiometabolic traits. Applications for projects that overlap significantly with protected projects may therefore require further discussion before approval.

External projects (open access and collaborations) that have been approved and have an access agreement in place are listed below (last updated 22 October 2025).

Principal investigator: Dr Christina Magnussen
Project title: Geographical distribution, global impact and related lifetime risk of classical cardiovascular risk factors on CVD onset
Date of first contact: 18/01/2021
MCPS data request id: 2021-001
Country: Germany
Type of data sharing agreement: Collaboration

Principal investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Data-driven socioeconomic clusters reveal inequalities in all-cause and cause specific mortality
Date of first contact: 10/05/2021
MCPS data request id: 2021-004
Country: 2021-004
Type of data sharing agreement: Open Access

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Prediabetes and cause-specific mortality
Date of first contact:18/05/2022
MCPS Data Request ID:2022-012-06
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Effect of sociodemographic determinants of social inequalities on preventable and treatable mortality
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-12
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Validation of an atherosclerotic disease-based prediction score for cardiometabolic mortality
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-15
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Lifestyle patterns and their interaction effect with metabolomic risk profiles on the risk of all-cause and cause-specific mortality
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-13
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Working occupations and their interaction with cardiometabolic risk profiles for all-cause and cause-specific mortality risk
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-16
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: External validation of AnthropoAge as a biological age metric for all-cause and cause-specific mortality
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-03
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Undiagnosed, untreated, and uncontrolled diabetes and high blood pressure and their risk of mortality from all causes
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-14
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Validation, calibration and metabolomic association of GFR equations in the Mexican population, its risk of mortality
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-05
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Clinical and sociodemographic determinants of newly diagnosed diabetes in apparently-healthy adults living in Mexico City
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-02
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: External validation of Globorisk, SCORE, Globorisk-LAC and the Framingham formula for cardiovascular disease and mortality
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-07
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Prediction of mortality using anthropometric indices (relative fat mass) and visceral adiposity indices
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-08
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Hypertension phenotypes, all-cause and cause-specific mortality
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-09
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Prediction of cardiovascular mortality according to diabetes endotypes in Mexican individuals
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-10
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Inception and validation of a predictive scale for cardiometabolic deaths using office, biochemical and metabolomic approach
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-11
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Metabolomic, anthropometric and sociodemographic characterization of accelerated anthropometric aging
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-04
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Smoking and cause-specific mortality in individuals with diabetes in Mexico: an analysis of the Mexico City Prospective Study
Date of first contact: 18/05/2022
MCPS Data Request ID: 2022-012-01
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Lorena Orozco
Project title: Leveraging the MCPS cohort: towards precision medicine and population genetics in Mexican/Latin American populations
Date of first contact: 29/06/2022
MCPS Data Request ID: 2022-004
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Yanink Caro-Vega
Project title: Female reproductive history and cancer-related deaths among participants in the Mexico City Prospective Study cohort
Date of first contact: 10/08/2022
MCPS Data Request ID: 2022-007
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Mashaal Sohail
Project title: Disentangling genes, environment, and their interplay in Mexico City
Date of first contact: 16/11/2022
MCPS Data Request ID: 2022-016-02
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Mashaal Sohail
Project title: Archaic introgression and complex trait variation in MCPS
Date of first contact: 16/11/2022
MCPS Data Request ID: 2022-016-01
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Gary O'Donovan
Project title: Longitudinal associations of the 'weekend warrior' and other physical activity patterns with mortality
Date of first contact: 17/11/2022
MCPS Data Request ID: 2022-015
Country: Colombia
Type of data sharing agreement: Open Access

Principal Investigator: Dr Gerson Ferrari
Project title: Role of modifiable risk factors on adverse health outcomes: a prospective study using the Mexico City Prospective Study
Date of first contact: 15/12/2022
MCPS Data Request ID: 2022-020
Country: Chile
Type of data sharing agreement: Open Access

Principal Investigator: Dr Claudia Gonzaga-Jauregui
Project title: Identification and analysis of medically actionable variants in the Mexican population
Date of first contact: 11/01/2023
MCPS Data Request ID: 2023-001-01
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Cristopher Van Hout
Project title: Parent of origin effects of genetic determinants of diabetic risk and related traits in the Mexico City Prospective Study
Date of first contact: 11/01/2023
MCPS Data Request ID: 2023-001-06
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Claudia Gonzaga-Jauregui
Project title: Identification and analysis of structural variation in the Mexican population
Date of first contact: 11/01/2023
MCPS Data Request ID: 2023-001-05
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Claudia Gonzaga-Jauregui
Project title: Identification and analysis of Mendelian disorders associated variation in the Mexican population
Date of first contact: 11/01/2023
MCPS Data Request ID: 2023-001-04
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Claudia Gonzaga-Jauregui
Project title: Identification of genetic variants associated with hereditary cancer in the Mexican population
Date of first contact: 11/01/2023
MCPS Data Request ID: 2023-001-03
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Claudia Gonzaga-Jauregui
Project title: Identification of genetic variants associated with Early Onset Alzheimer's Disease risk in the Mexican population
Date of first contact: 11/01/2023
MCPS Data Request ID: 2023-001-02
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Enrique Gomez-Figueroa
Project title: Stroke mortality and risk factors in Mexico
Date of first contact: 19/01/2023
MCPS Data Request ID: 2023-005
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Adrian Soto-Mota
Project title: Mortality across different levels of LDL-C in people without other cardiovascular risk factors
Date of first contact: 01/02/2023
MCPS Data Request ID: 2023-008
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Vicente Diego Ortega-Del Vecchyo
Project title: Impact of natural selection acting on new variants on the MCPS
Date of first contact: 16/03/2023
MCPS Data Request ID: 2023-011
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Yang Luo
Project title: HLA typing, diversity, and association analysis in the Mexico City Prospective Study
Date of first contact: 16/03/2023
MCPS Data Request ID: 2023-012
Country: UK
Type of data sharing agreement: Oxford Interdepartmental

Principal Investigator: Dr Cristopher Van Hout
Project title: Modelling the relationship between obesity and cancer in the Mexico City Prospective Study
Date of first contact: 31/03/2023
MCPS Data Request ID: 2023-001-07
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Claudia Gonzaga-Jauregui
Project title: Identification and analysis of short tandem repeats and their variability in Mexican genomes
Date of first contact: 12/04/2023
MCPS Data Request ID: 2023-001-09
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Claudia Gonzaga-Jauregui
Project title: Identification of pharmacogenomic variants associated with drug response and metabolism in the Mexican population
Date of first contact: 12/04/2023
MCPS Data Request ID: 2023-001-08
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Osvaldo Máximo Mutchinick Baringoltz
Project title: Development of a risk prediction model for myelomeningocele using a candidate gene sequencing panel in Mexican mestizo
Date of first contact: 05/06/2023
MCPS Data Request ID: 2023-023
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Leveraging rare variation, global and local ancestry to develop polygenic risk scores for type 2 diabetes in admixed Americans
Date of first contact: 07/06/2023
MCPS Data Request ID: 2023-021
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Gary O'Donovan
Project title: What are the associations between ‘diabesity’ and mortality in adults in Mexico? Findings from the Mexico City Prospective Study
Date of first contact: 14/08/2023
MCPS Data Request ID: 2023-026
Country: Colombia
Type of data sharing agreement: Open Access

Principal Investigator: Dr Lorena Orozco
Project title: Genetic variants associated with the response to diabetes type 2 treatment
Date of first contact: 25/08/2023
MCPS Data Request ID: 2023-028
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Fanny Petermann-Rocha
Project title: Associations between the ‘weekend warrior’ physical activity pattern and screen-detected mild cognitive impairment
Date of first contact: 25/08/2023
MCPS Data Request ID: 2023-027
Country: Chile
Type of data sharing agreement: Open Access

Principal Investigator: Dr Catalina Medina Garcia
Project title: Are there U-shaped associations of HDL-cholesterol and HDL-cholesterol subclasses with mortality?
Date of first contact: 07/09/2023
MCPS Data Request ID: 2023-029
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Malaquías López Cervantes
Project title: Family characteristics related to the presence of obesity in residents of Mexico City
Date of first contact: 19/09/2023
MCPS Data Request ID: 2023-031
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Prof Peter Visscher
Project title: Estimation of between-ancestry genetic differences from analysis of family data in an admixed population
Date of first contact: 07/12/2023
MCPS Data Request ID: 2023-036
Country: UK
Type of data sharing agreement: Oxford Interdepartmental

Principal Investigator: Prof Gregorio Obrador Vera
Project title: Prevalence, Management, and Mortality Outcomes of CKD in the Mexico City Prospective Study
Date of first contact: 29/01/2024
MCPS Data Request ID: 2024-004
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Elizabeth Atkinson
Project title: A collaboration to test TRACTOR-MIX on MCPS data
Date of first contact: 05/02/2024
MCPS Data Request ID: 2024-006
Country: USA
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Gary O'Donovan
Project title: Associations between screen-detected cognitive impairment and mortality: findings from the Mexico City Prospective Study
Date of first contact: 07/02/2024
MCPS Data Request ID: 2024-007
Country: Colombia
Type of data sharing agreement: Collaboration

Principal Investigator: Evelia Apolinar-Jiménez
Project title: Associations of the American Heart Association’s Life’s Essential 8 score with morbidity and mortality in Mexico
Date of first contact: 19/03/2024
MCPS Data Request ID: 2024-009
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Gerson Ferrari
Project title: Joint association between physical activity, obesity and all cause and cause specific mortality in Mexican adults
Date of first contact: 21/03/2024
MCPS Data Request ID: 2024-011
Country: Chile
Type of data sharing agreement: Open Access

Principal Investigator: Prof Janitza L. Montalvo-Ortiz
Project title: Comprehensive functional analysis of copy number variants in Major Depressive Disorder in Latin American population
Date of first contact: 26/04/2024
MCPS Data Request ID: 2024-012
Country: USA
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Adrian Rubli
Project title: Genetic moderation of the income-health relationship: Evidence from Mexico's elderly cash transfer program
Date of first contact: 07/05/2024
MCPS Data Request ID: 2024-013
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Javier Calvo Marin
Project title: Analysis of Cardiovascular Risk Factor and Mortality Among the Elderly in Mexico City and Costa Rica: Insights from the MCPS and Costa Rica cohorts
Date of first contact: 03/07/2024
MCPS Data Request ID: 2024-025
Country: Costa Rica
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Gerson Ferrari
Project title: Joint association of physical activity and sleep duration with all-cause and cause-specific mortality: a prospective study
Date of first contact: 09/07/2024
MCPS Data Request ID: 2024-026
Country: Chile
Type of data sharing agreement: Open Access

Principal Investigator: Dr Carolina Ochoa Rosales
Project title: Biomarkers of Allostatic Load in Dementia: A Systematic Review and Meta-Analysis
Date of first contact: 30/07/2024
MCPS Data Request ID: 2024-030
Country: Chile
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Gerson Ferrari
Project title: Physical activity pattern and all-cause mortality: a prospective study of 150,145 Mexican adults with different health conditions
Date of first contact: 31/07/2024
MCPS Data Request ID: 2024-029
Country: Chile
Type of data sharing agreement: Open Access

Principal Investigator: Valerie Gunchick
Project title: Genome-wide association study (GWAS) for biliary tract cancer (BTC)
Date of first contact: 01/08/2024
MCPS Data Request ID: 2024-032
Country: USA
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Carolina Ochoa Rosales
Project title: Metabolites associated with cognitive impairment or dementia in Latin America: a systematic review and meta-analysis
Date of first contact: 01/08/2024
MCPS Data Request ID: 2024-031
Country: Chile
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Josep Mercader
Project title: G6PD and diabetes complications
Date of first contact: 23/08/2024
MCPS Data Request ID: 2024-037-01
Country: USA
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Josep Mercader
Project title: Assessing pathogenicity of monogenic diabetes genes using sequence/TOPMed imputed data
Date of first contact: 23/08/2024
MCPS Data Request ID: 2024-037-03
Country: USA
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Fanny Petermann-Rocha
Project title: Latent class analysis of multimorbidity and its associations with cardiovascular disease, cancer and all-cause mortality in Mexican adults
Date of first contact: 29/08/2024
MCPS Data Request ID: 2024-036
Country: Chile
Type of data sharing agreement: Open Access

Principal Investigator: Dr Catalina Medina Garcia
Project title: Frailty index and its association with cardiovascular disease and all-cause mortality in Mexican adults: findings from the Mexico City Prospective Study
Date of first contact: 09/09/2024
MCPS Data Request ID: 2024-038
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Prof Janitza L. Montalvo-Ortiz
Project title: Meta-analysis of genome-wide association studies of smoking traits in the Latin American Genomics Consortium (LAGC)
Date of first contact: 09/09/2024
MCPS Data Request ID: 2024-041
Country: USA
Type of data sharing agreement: Collaboration

Principal Investigator: Prof Paolo Boffetta
Project title: Using large-scale cohort studies to identify lifetime, environmental and occupational determinants of healthy ageing
Date of first contact: 19/09/2024
MCPS Data Request ID: 2024-042
Country: Italy
Type of data sharing agreement: Open Access

Principal Investigator: Dr Gretchen Saunders
Project title: Collaboration with GSCAN (GWAS & Sequencing Consortium of alcohol and Nicotine use)
Date of first contact: 01/11/2024
MCPS Data Request ID: 2024-046
Country: USA
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Steven Hageman
Project title: Systematic recalibration and external validation of the SCORE2 risk model to the Latin American clinical practice
Date of first contact: 04/11/2024
MCPS Data Request ID: 2024-045
Country: The Netherlands
Type of data sharing agreement: Collaboration

Principal Investigator: Rodrigo Garcia-Cerde
Project title: Transgenerational Impacts of Social Determinants of Health in Mexican Adults: A Cohort-Based Study
Date of first contact: 11/11/2024
MCPS Data Request ID: 2024-047
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Enrique Gomez-Figueroa
Project title: Development of a Predictive Model for Cerebrovascular Mortality Using Medical Data from MCPS: Integrating Machine Learning
Date of first contact: 18/11/2024
MCPS Data Request ID: 2024-048
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Ruth Selene Fuentes Garcia
Project title: Risk equations for complications related to Type 2 Diabetes Mellitus
Date of first contact: 05/12/2024
MCPS Data Request ID: 2024-051
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Lorena Orozco
Project title: Mitochondrial biomarkers and cardiometabolic diseases: MCPS cohort
Date of first contact: 17/12/2024
MCPS Data Request ID: 2024-052
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Gerson Ferrari
Project title: Association of plasma metabolites, lifestyle risk factors and cardiometabolic conditions with all-cause and cause-specific mortality
Date of first contact: 30/01/2025
MCPS Data Request ID: 2025-005
Country: Chile
Type of data sharing agreement: Open Access

Principal Investigator: Dr Gerson Ferrari
Project title: Genetic composition and physical activity levels in Mexican adults
Date of first contact: 30/01/2025
MCPS Data Request ID: 2025-006
Country: Chile
Type of data sharing agreement: Open Access

Principal Investigator: Dr Edgar Denova Gutierrez
Project title: Omega-3 and omega-6 polyunsaturated fatty acids and the risk of all-cause and cause-specific mortality in the Mexico City Prospective Study
Date of first contact: 04/02/2025
MCPS Data Request ID: 2025-008
Country: USA
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Fabiola Mabel Del Razo Olvera
Project title: Gene-Environment Interaction: Impact of the SLC16A11 Haplotype, ABCA1 and HNF1A variants on Metabolic Diseases
Date of first contact: 07/04/2025
MCPS Data Request ID: 2025-015
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Ana Lucía Yáñez Félix
Project title: Analysis of the Allelic Frequency of Single Nucleotide Variants in Genes Related to Coagulation Disorders Based on Databases of the Mexican population
Date of first contact: 05/05/2025
MCPS Data Request ID: 2025-030
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Dr Wenjian Bi
Project title: Scalable, accurate, and universal analysis frameworks for large-scale genetic association studies in an admixed population
Date of first contact: 07/05/2025
MCPS Data Request ID: 2025-039
Country: China
Type of data sharing agreement: Open Access

Principal Investigator: Dr Xiang Gao
Project title: Gene–Metabolite Interactions in the Development of metabolic diseases
Date of first contact: 14/05/2025
MCPS Data Request ID: 2025-047
Country: China
Type of data sharing agreement: Open Access

Principal Investigator: Duncan Robertson
Project title: Enhancing analysis of demographic history and complex traits in the MCPS cohort using ancestral recombination graphs
Date of first contact: 16/05/2025
MCPS Data Request ID: 2025-050
Country: UK
Type of data sharing agreement: Oxford Interdepartmental

Principal Investigator: Dr Daniel Benjamín Elías López
Project title: Prevalence and Phenotypic Expression of Dysbetalipoproteinemia in Mexican Population and Its Association with cardiovascular outcomes
Date of first contact: 02/06/2025
MCPS Data Request ID: 2025-056
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Prof Johannes Kettunen
Project title: Trans-ethnic GWAS meta-analysis of NMR metabolic traits
Date of first contact: 18/06/2025
MCPS Data Request ID: 2025-060
Country: Finland
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Evaluating the utility of integrating genomic data into diabetes subtype classifications to predict cardiovascular risk
Date of first contact: 25/06/2025
MCPS Data Request ID: 2025-058
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Omar Yaxmehen Bello-Chavolla
Project title: Characterizing the genomic architecture and pathophysiology of biological and accelerated aging in Mexican adults using MCPS data
Date of first contact: 25/06/2025
MCPS Data Request ID: 2025-059
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Ana Luisa Sosa Ortiz
Project title: Exploration and comparison of exposure to air pollutants and occupation in two boroughs of Mexico City and their association with mortality
Date of first contact: 25/08/2025
MCPS Data Request ID: 2025-071
Country: Mexico
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Stefan Blankenburg
Project title: Target-trial emulation of blood-pressure–mediated cardiovascular risk reduction in the general population
Date of first contact: 27/08/2025
MCPS Data Request ID: 2025-081-02
Country: Germany
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Stefan Blankenburg
Project title: Global Effect of Modifiable Lipid Concentrations on Cardiovascular Risk and All-Cause Mortality in the Population
Date of first contact: 27/08/2025
MCPS Data Request ID: 2025-081-03
Country: Germany
Type of data sharing agreement: Collaboration

Principal Investigator: Dr Cristopher Van Hout
Project title: Current methods in epidemiology for the identification of relevant factors and risk prediction of common diseases in a Mexico cohort
Date of first contact: 04/09/2025
MCPS Data Request ID: 2025-075
Country: Mexico
Type of data sharing agreement: Open Access

Principal Investigator: Prof Johannes Kettunen
Project title: The role of PKHD1L1 in female infertility
Date of first contact: 22/09/2025
MCPS Data Request ID: 2025-082
Country: Finland
Type of data sharing agreement: Collaboration

Principal Investigator: Prof Inês Barroso
Project title: The Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)
Date of first contact: 22/09/2025
MCPS Data Request ID: 2025-079
Country: UK
Type of data sharing agreement: Collaboration

References

  1. Alegre-Díaz, Herrington, López-Cervantes et al. Diabetes and cause-specific mortality in Mexico City. New Engl J Med 2016; 375: 1961-1971.
  2. Herrington, Alegre-Díaz, Wade et al. Effect of diabetes duration and glycaemic control on 14-year cause-specific mortality in Mexican adults: a blood-based prospective cohort study. Lancet Diab Endocrinol 2018; 6: 455-463.
  3. Bragg, Kuri-Morales, Berumen et al. Diabetes and infectious disease mortality in Mexico City. BMJ Open Diab Res Care 2023; 11: e003199.
  4. Bragg, Kuri-Morales, Trichia et al. Type 2 diabetes and cause-specific mortality in Mexico City: a Mendelian randomization analysis. Lancet Reg Health Am 2025; 45: 101082.
  5. Fermín-Martínez, Yaxmehen Bello-Chavolla, Daniel Paz-Cabrera et al. Prediabetes and risk of all-cause and cause-specific mortality: a prospective study of 114,062 adults in Mexico City. J Clin Endocrinol Metab 2025 dgaf225.
  6. Gnatiuc, Alegre-Díaz, Wade et al. General and abdominal adiposity and mortality in Mexico City: prospective study of 150 000 Adults. Ann Int Med 2019; 171: 397-405.
  7. Gnatiuc, Tapia-Conyer, Wade et al. Abdominal and gluteo-femoral markers of adiposity and risk of vascular-metabolic mortality in a prospective study of 150 000 Mexican adults. Eur J Prev Cardiol 2022: 29(5); 730-8.
  8. Alegre-Díaz, Friedrichs, Ramirez-Reyes et al. Body mass index and COVID-19 mortality: prospective study of 120 000 Mexican adults. Int J Epidemiol 2022;51(5):1698-700.
  9. Gnatiuc Friedrichs, Wade, Alegre-Díaz et al. Body composition and risk of vascular-metabolic mortality risk in 113 000 Mexican men and women without prior chronic disease. J Am Heart Assoc. 2023 Jan 25: e028263.
  10. Gnatiuc Friedrichs, Kuri-Morales, Trichia et al. A Mendelian Randomization study of the effect of body mass index on 52 causes of death among 125,000 Mexican adults with admixed ancestry. Int J Epidemiol 2025: 54; 4: dyaf110.
  11. Tapia-Conyer, Alegre-Díaz, Gnatiuc et al. Association of blood pressure with cause-specific mortality in Mexican adults. JAMA Network Open. 2020; 3: e201814.
  12. Turner, Kuri-Morales, Alegre-Díaz, et al. Blood Pressure and Mortality in Mexico City: A Mendelian Randomization Study. Hypertension. Published online September 17, 2025. doi:10.1161/HYPERTENSIONAHA.125.25348.
  13. Thomson, Tapia-Conyer, Lacey et al. Low-intensity daily smoking and cause-specific mortality in Mexico: prospective study of 150,000 adults. Int J Epidemiol 2021; 50: 955-64.
  14. Addey, Alegre-Díaz, Bragg et al. Educational and social inequalities and cause-specific mortality in Mexico City: a prospective study. Lancet Public Health 2023; 8(9): e670-e679.
  15. Trichia, Alegre-Díaz, Aguilar-Ramirez et al. Alcohol and mortality in Mexico: prospective study of 150 000 adults. Lancet Pub Health 2024; 9(11): e907-e915.
  16. Kuri-Morales, Emberson, Alegre Díaz et al. The prevalence of chronic diseases and major disease risk factors at different ages among 150 000 men and women living in Mexico City: cross-sectional analyses of a prospective study. BMC Public Health 2009, 9: 9.
  17. Aguilar-Ramirez, Alegre-Díaz, Gnatiuc et al. Changes in the diagnosis and management of diabetes in Mexico City between 1998-2004 and 2015-19. Diabetes Care 2021;44(4): 944-51
  18. Gnatiuc, Alegre-Díaz, Halsey et al. Adiposity and blood pressure in 110 000 Mexican adults. Hypertension 2017; 69: 608-14.
  19. González-Carballo, Kuri-Morales, Chiquete et al. Cognitive impairment at older ages among 8000 men and women living in Mexico City: cross-sectional analyses of a prospective study. BMC Public Health 2024; 24: 3620.
  20. Aguilar-Ramirez, Alegre-Díaz, Herrington et al. Association of kidney function with NMR-quantified lipids, lipoproteins, and metabolic measures in Mexican adults. J Clin Endocrinol Metab 2021; 106(10): 2828-39.
  21. Aguilar-Ramirez, Herrington, Alegre-Díaz et al. Adiposity and NMR-measure lipid and metabolic biomarkers among 30,000 Mexican adults. Commun Med 2022; 2: 143.
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