Cytogenetics of childhood Acute Myeloid Leukemia: United Kingdom Medical Research Council treatment trials AML 10 and 12
Harrison CJ., Hills RK., Moorman AV., Grimwade DJ., Hann IM., Webb DKH., Wheatley K., Graff SSND., Berg EVD., Burnett AK., Gibson BES.
Karyotype is an independent indicator of prognosis in acute myeloid leukemia (AML) that is widely applied to risk-adapted therapy. Because AML is rare in children, the true prognostic significance of individual chromosomal abnormalities in this age group remains unclear