UNLABELLED: A program package to enable genome-wide association of copy number variants (CNVs) with quantitative phenotypes in families of arbitrary size and complexity. Intensity signals that act as proxies for the number of copies are modeled in a variance component framework and association with traits is assessed through formal likelihood testing. AVAILABILITY AND IMPLEMENTATION: The Java package is made available at www.imperial.ac.uk/medicine/people/m.falchi/. CONTACT: m.falchi@imperial.ac.uk.

Original publication

DOI

10.1093/bioinformatics/btr264

Type

Journal article

Journal

Bioinformatics

Publication Date

01/07/2011

Volume

27

Pages

1873 - 1875

Keywords

DNA Copy Number Variations, Disease, Family, Gene Frequency, Genome-Wide Association Study, Humans, Phenotype, Quantitative Trait, Heritable, Software