Association of physical activity and cardiometabolic risk in children 3-12 years
Vanderloo LM., Maguire JL., Dai DWH., Parkin PC., Borkhoff CM., Tremblay MS., Anderson LN., Birken CS., Cohn R., Lau E., Laupacis A., Salter M., Szatmari P., Weir S., Keown-Stoneman C., Kowal C., Mason D., Abdurrahman M., Anderson K., Arbess G., Baker J., Barozzino T., Bergeron S., Bhagat D., Bloch G., Bonifacio J., Bowry A., Calpin C., Campbell D., Cheema S., Cheng E., Chisamore B., Constantin E., Danayan K., Das P., Derocher MB., Do A., Doukas K., Egger A., Farber A., Freedman A., Freeman S., Gazeley S., Guiang C., Ha D., Handford C., Hanson L., Harrington L., Jacobson S., Jagiello L., Jansz G., Kadar P., Kim F., Kiran T., Knowles H., Kwok B., Lakhoo S., Lam-Antoniades M., Lau E., Leduc D., Leung FH., Li A., Li P., Malach J., Male R., Mascoll V., Meret A., Mok E., Moodie R., Nader M., Nash K., Naymark S., Owen J., Peer M., Pena K., Perlmutar M., Persaud N., Pinto A., Porepa M., Qi V., Ramji N., Ramji N., Raza D., Rosenthal A., Rouleau K., Ruderman C., Saunderson J., Schiralli V., Sgro M., Shuja H., Shepherd S., Smiltnieks B., Srikanthan C., Taylor C., Treherne S., Turner S., Uddin F., van den Heuvel M., Vaughan J., Weisdorf T.
Background: This study aimed to examine the association between physical activity (PA) and a total cardio metabolic risk (CMR) score in children aged 3-12 years. Secondary objectives were to examine the association between PA and individual CMR factors. Methods: A longitudinal study with repeated measures was conducted with participants from a large primary care practice-based research network in Toronto, Canada. Mixed effects models were used to examine the relationship between parent-reported physical activity and outcome variables (total CMR score, triglycerides, glucose, high-density lipoprotein cholesterol, systolic blood pressure, waist circumference, weight-to-height ratio, and non-high-density lipoprotein cholesterol). Results: Data from 1885 children (6.06 y, 54.4% male) with multiple visits (n = 2670) were included in the analyses. For every unit increase of 60 minutes of PA, there was no evidence of an association with total CMR score (adjusted: −0.02 [−0.014 to 0.004], P =.11]. For the individual CMR components, there was evidence of a weak association between PA and systolic blood pressure (−0.01 [−0.03 to −0.01], P