Professor Robert Clarke
- BEST-D: Biochemical Efficacy and Safety Trial of Vitamin D
- China Kadoorie Biobank
- HPS: Heart Protection Study
- PROCARDIS Sibling-pair Studies of Genetic Determinants of MI
- Re-survey and Follow-up of 1970 Whitehall Study
- SEARCH: Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine
MD, FRCP, FFPH, FFPHI, MSc, DCH
Professor of Epidemiology and Public Health Medicine
- Clinical Trial Service Unit and Epidemiological Studies Unit
Robert Clarke is a Professor of Epidemiology and Public Health Medicine at the Clinical Trial Service Unit (CTSU), Nuffield Department of Population Health, University of Oxford and Consultant in Public Health Medicine and Director of the MSc course in Global Health Science. He qualified in clinical medicine in Ireland and worked for 5 years in internal medicine and 4 years in cardiology. After 2 years in clinical pharmacology at Vanderbilt University, Nashville, USA, he joined CTSU in 1991 and specialised in Cardiovascular Epidemiology.
His main research interests are to understand the importance of classical and novel risk factors for occlusive vascular diseases. He led several large observational studies and meta-analyses of observational studies and randomized trials (eg, Whitehall study, PROCARDIS, CARDIoGRAMplusC4D, B-Vitamin Treatment Trialists’ Collaboration and the BEST-D trial). He also worked extensively on the Prospective Studies Collaboration and the China Kadoorie Biobank (CKB) study. He currently leads a research programme to assess the importance of blood pressure, blood lipids, and novel biomarkers (including genetic markers, cytokines, proteomics and metabolomics) for occlusive vascular diseases in the CKB study. His work has been widely cited (200 publications, H-index of 54) and is listed in Tomson Reuters’ Most Influential Scientific Minds 2014.
Importance of healthy lifestyle factors and ideal cardiovascular health metrics for risk of heart failure in Chinese adults.
Yang R. et al, (2021), Int J Epidemiol
Adiposity, metabolomic biomarkers and risk of nonalcoholic fatty liver disease: a case-cohort study.
Pang Y. et al, (2021), Am J Clin Nutr
Improved prediction of fracture risk leveraging a genome-wide polygenic risk score
Lu T. et al, (2021), Genome Medicine, 13
Gender differences in modifiable risk factors for hip fracture: 10-year follow-up of a prospective study of 0.5 million Chinese adults
CLARKE R. et al, (2021), Journal of Internal Medicine
Hospital management of major stroke types in Chinese adults: a population-based study of 20 000 hospitalised stroke cases.
Qin H. et al, (2021), BMJ Open, 11