Bruno da Costa
PhD
Senior Scientist
Dr. Bruno R. da Costa is a senior scientist at the Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU) and an Associate Professor of Clinical Epidemiology at the University of Toronto.
In 2023, he joined CTSU, where he co-leads the development of a clinical trial methods research programme and serves as trial statistician for various clinical trials. His research focuses on the comparative effectiveness of interventions in cardiovascular and musculoskeletal medicine and on clinical research methods. He has led several influential studies that impacted clinical practice guidelines for osteoarthritis care.
Since 2009, Bruno has worked as a methodologist and statistician, contributing to the design and analysis of numerous clinical trials, observational studies, and meta-analyses. He was a research fellow at the Institute of Social and Preventive Medicine and a statistician at CTU Bern, the University of Bern’s clinical trials unit from 2009 to 2014. Later, he served as the head of statistics and methodology at the Institute of Primary Health Care and the Department of Cardiology at the University of Bern from 2015 to 2017.
In 2017, Dr. da Costa moved to Toronto to become the Associate Director of the Applied Health Research Centre (AHRC) and Assistant Professor of Clinical Epidemiology at the University of Toronto. He was promoted to Associate Professor in 2019 and served as the Acting Director of the AHRC between 2020 and 2022.
He holds a PhD in Clinical Epidemiology and Biostatistics from the University of Bern in Switzerland, along with MSc degrees in Medical Statistics from the University of Leicester in the UK and Physiotherapy from the University of Alberta in Canada.
Recent publications
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Aortic valve replacement versus conservative treatment in asymptomatic severe aortic stenosis: long-term follow-up of the AVATAR trial
Journal article
Banovic M. et al, (2024), European Heart Journal
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Effectiveness and safety of intra-articular interventions for knee and hip osteoarthritis based on large randomised trials: a systematic review and network meta-analysis
Journal article
Pereira TV. et al, (2024), Osteoarthritis and Cartilage
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Evidence-based hierarchy of pain outcome measures for osteoarthritis clinical trials and meta-analyses
Journal article
Saadat P. et al, (2024), Osteoarthritis and Cartilage
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De-escalation to ticagrelor monotherapy versus 12 months of dual antiplatelet therapy in patients with and without acute coronary syndromes: a systematic review and individual patient-level meta-analysis of randomised trials.
Journal article
Valgimigli M. et al, (2024), Lancet
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Factors Associated With Loss to Follow-Up in Surgical Trials: A Systematic Review and Meta-Analysis
Journal article
Walker RJB. et al, (2024), Journal of Surgical Research, 300, 33 - 42