Proteomic profiling identifies novel independent relationships between inflammatory proteins and myocardial infarction.
Valdes-Marquez E., Clarke R., Hill M., Watkins H., Hopewell JC., PROCARDIS Consortium None.
BACKGROUND: Inflammation has been implicated in the pathogenesis of coronary heart disease (CHD), but the relevance and independence of individual inflammatory proteins is uncertain. OBJECTIVE: To examine the relationships between a spectrum of inflammatory proteins and myocardial infarction (MI). METHODS: A panel of 92 inflammatory proteins was assessed using an OLINK multiplex immunoassay among 432 MI cases (diagnosed