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Congratulations to NHS Forth Valley who enrolled the final participant to join the LENS trial (on 27th July 2021). Our amazing sites have randomized 1151 participants between them across all mainland NHS Scotland Health Boards.



You may be interested to read the article by Dr Caroline Wood (University of Oxford) which describes some of the challenges that have arisen conducting clinical trials of treatments for chronic disease in the time of COVID-19. Various features of the LENS trial, and the heroic efforts of the study team in Oxford and across Scotland, have meant that the study has continued to progress well despite these difficult circumstances. You can find the article at:


questionnaires on visual function and quality of life

Participants who have been taking part in LENS for over 2 years will receive a couple of questionnaires in the post. The first questionnaire (called the VFQ-25) asks about your vision. The second questionnaire (called the EQ-5D) asks about your quality of life. These are the same questionnaires that you completed at the very start of the trial.

The information that we collect in these forms is very important to the trial, and we greatly appreciate you taking the time to complete them and send them back to us by FREEPOST. If you have any questions about how to complete either of the questionnaires, please do not hesitate to give us a call. Thank you for your ongoing support for LENS.


COVID-19 related information

For LENS participants who have already been randomized: you will continue to receive study medication by Royal Mail and you will receive your usual six monthly telephone contact from a LENS research nurse

For LENS participants who have attended a screening visit (but not yet been randomized): you will receive your study treatment by Royal Mail, and a LENS research nurse will be in contact by telephone in due course

For patients who have been invited to join the trial, but not yet attended a screening visit: a member of the LENS team will be in touch in the coming months. Some hospitals are not able to conduct face-to-face visits at present 





 Insight - LENS trial newsletter Volume 1




 Insight - LENS trial newsletter Volume 2