Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Breast reconstruction has become increasingly popular over the past 20 years. There is concern that it may mask locoregional recurrence or that immediate reconstruction may compromise adjuvant treatments. We review available evidence regarding its oncological safety. The literature consists almost entirely of single institution, small retrospective reviews with variable follow-up and varying conclusions. Most reviews suggest that breast reconstruction does not adversely affect disease-free or overall survival and that there is no significant delay in presentation with recurrent disease. Three retrospective series compared chemotherapy delivery after immediate breast reconstruction with controls having mastectomy alone. No delay in chemotherapy delivery or effect on dose intensity was demonstrated. Irradiation of a prosthetic implant has been shown to increase the rate of capsular contracture; irradiation of autogenous tissue reconstruction is usually well tolerated.

Original publication

DOI

10.1016/j.breast.2004.08.006

Type

Journal article

Journal

Breast

Publication Date

04/2005

Volume

14

Pages

118 - 130

Keywords

Breast Implants, Breast Neoplasms, Chemotherapy, Adjuvant, Female, Humans, Mammography, Medical Oncology, Neoadjuvant Therapy, Neoplasm Recurrence, Local, Patient Care Planning, Prognosis, Radiotherapy, Adjuvant, Reconstructive Surgical Procedures, Risk Factors, Survival Analysis