Estimation of life expectancies using continuous-time multi-state models.
van den Hout A., Sum Chan M., Matthews F.
BACKGROUND AND OBJECTIVE: There is increasing interest in multi-state modelling of health-related stochastic processes. Given a fitted multi-state model with one death state, it is possible to estimate state-specific and marginal life expectancies. This paper introduces methods and new software for computing these expectancies. METHODS: The definition of state-specific life expectancy given current age is an extension of mean survival in standard survival analysis. The computation involves the estimated parameters of a fitted multi-state model, and numerical integration. The new R package elect provides user-friendly functions to do the computation in the R software. RESULTS: The estimation of life expectancies is explained and illustrated using the elect package. Functions are presented to explore the data, to estimate the life expectancies, and to present results. CONCLUSIONS: State-specific life expectancies provide a communicable representation of health-related processes. The availability and explanation of the elect package will help researchers to compute life expectancies and to present their findings in an assessable way.