CTSU Projects
Large-scale randomised evidence
The need for large-scale randomised evidence
Large streamlined "mega-trials"
(ASCEND) A Study of Cardiovascular Events iN Diabetes
(ATLAS) Adjuvant Tamoxifen -- Longer Against Shorter (ATLAS home page)
(COMMIT/CCS-2) ClOpidogrel and Metoprolol in Myocardial Infarction Trial
(DEVTA) De-worming and Enhanced Vitamin A
(HPS) MRC/BHF Heart Protection Study
(PEP) Pulmonary Embolism Prevention trial
(SEARCH) Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine
(SHARP) Study of Heart and Renal Protection
- (THRIVE) Heart attack, stroke and HDL Cholesterol
Chinese colorectal cancer trial
Chinese breast cancer trial
Hepatitis B vaccine trial
Leukaemia trials:
CLL4 (closed to new registrations on 31st October 2004)
Development of large, simple trials in neuropsychiatric disease
General development of trials
Large collaborative "meta-analyses" of trials
(ATT) Antithrombotic Trialists' Collaboration
(CTT) Cholesterol Treatment Trialists' Collaboration
(EBCTCG) Early Breast Cancer Trialists' Collaborative Group
(FTT) Fibrinolytic Therapy Trialists' Collaborative Group
(PCTCG) Prostate Cancer Trialists Collaborative Group
Collaborative meta-analyses of leukaemia trials
(CNT) Coxib and traditional NSAID Trialists' Collaboration
Large-scale observational epidemiology
The need for large-scale observational epidemiology
Large collaborative meta-analyses of observational studies
(PSC) Prospective Studies Collaboration
World pooling of case-control studies of residential radon and lung cancer
Large retrospective, prospective or descriptive studies
COBS (Collaborative Group on Observational Studies of Breast Cancer Survivors)
ISIS case-control study of the determinants of MI
ISIS and PROCARDIS sibling-pair studies of genetic determinants of MI
Kadoorie Study of Chronic Disease in China (KSCDC)
Large-scale retrospective studies of smoking and death in China
Large-scale retrospective studies of smoking and death in India
Other large prospective studies in developing populations
Other large retrospective studies in developing populations
Prospective blood-based study of 150,000 adults in Mexico
Prospective study of 500,000 adults in Chennai, India
Prospective study in 250,000 middle-aged Chinese adults
Re-survey and follow-up of 1970 Whitehall Study (7000 elderly individuals)
External trials
We provide randomisation services for the following trials:
(ACST) Asymptomatic carotid surgery trial
(BALANCE) Maintenance treatment in bipolar disorder
(CAESAR) Caesarian section surgical techniques: a randomised factorial trial
(CRASH) Corticosteroid randomisation after significant head injury
(INNOVO) Trial of ventilatory support with inhaled nitrous oxide versus ventilatory support without inhaled nitrous oxide
(ISAT) International subarachnoid aneurysm trial
(MAGPIE) Magnesium sulphate for treatment of pre-eclampsia: a trial to evaluate the effects on women and their babies
(MIST) Miscarriage trial
(QUASAR) Quick simple and reliable (trial in colorectal cancer)
(SST) Spine stabilisation trial
(STICH) Surgical trial in intracerebral haemorrage
(TEAMS) Trial of the effects of antenatal multiple courses of steroids versus a single course
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